Invitrogen
Catalog # MA1-23350
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:1,000 |
Species reactivity | Human |
Host / Isotype | Mouse / IgG2a |
Class | Monoclonal |
Type | Antibody |
Clone | 4126 |
Immunogen | Amino terminal fragment of human Rad1 purified from E. coli. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | Protein G |
Storage buffer | PBS, pH 7, with 20% glycerol |
Contains | no preservative |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_560814 |
Recommended positive controls: 293T, A431, HeLa, HepG2.
Rad1 is a component of a heterotrimeric PCNA-like complex that contains Rad9 and Hus1 proteins. This complex is involved in the 9-1-1 cell cycle checkpoing response complex that plays a major role in DNA repair, by associating with Rad17 and several components of the PCNA-loading heteropentamer replication factor C. Mutants has been shown to partially restore radiation resistance and G2-checkpoint activity. It has also been shown to possess exonuclease activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cell cycle checkpoint protein Hrad1; Cell cycle checkpoint protein RAD1; checkpoint control protein HRAD1; DNA repair exonuclease rad1 homolog; DNA repair exonuclease REC1; exonuclease homolog RAD1; hRAD1; RAD1 checkpoint clamp component; RAD1 homolog; Rad1-like DNA damage checkpoint protein
Gene Aliases: HRAD1; RAD1; REC1
UniProt ID: (Human) O60671
Entrez Gene ID: (Human) 5810
Molecular Function:
DNA metabolism protein
exodeoxyribonuclease
nucleic acid metabolism protein
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