Invitrogen
This Antibody was verified by Knockout to ensure that the antibody binds to the antigen stated. View details.
Catalog # MA1-172
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Flow Cytometry (Flow) | 5-20 µg/mL |
Immunoprecipitation (IP) | Assay-dependent |
Western Blot (WB) | 0.5-2 µg/mL |
Species reactivity | Human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Clone | 4D3F11 |
Immunogen | Recombinant full length protein corresponding to Human RAB27A aa 1-221. Expressed in E. coli. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | Protein A |
Storage buffer | PBS, pH 7.4, with 1mg/mL BSA, 30% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2608617 |
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GTP-binding protein Ram; mutant Ras-related protein Rab-27A; Rab-27; Ras-related protein Rab-27A
Gene Aliases: GS2; HsT18676; RAB27; RAB27A; RAM
UniProt ID: (Human) P51159
Entrez Gene ID: (Human) 5873
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