Invitrogen
Catalog # PA5-40189
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:500-1:2,000 |
Immunocytochemistry (ICC/IF) | 1:20-1:100 |
Species reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthesized peptide derived from human ESPL1 around phosphorylation site of S1126. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 50% glycerol |
Contains | 0.02% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2607835 |
Caspase-like protease, which plays a central role in the chromosome segregation by cleaving the SCC1/RAD21 subunit of the cohesin complex at the onset of anaphase. During most of the cell cycle, it is inactivated by different mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Caspase-like protein ESPL1; extra spindle pole bodies 1, separase; extra spindle pole bodies homolog 1; extra spindle poles like 1; Extra spindle poles-like 1 protein; FLJ46492; Separase; Separin; separin, cysteine protease
Gene Aliases: ESP1; ESPL1; KIAA0165; SEPA
UniProt ID: (Human) Q14674
Entrez Gene ID: (Human) 9700
Molecular Function:
cysteine protease
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