Invitrogen
Catalog # PA5-40176
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | 1:50-1:100 |
Western Blot (WB) | 1:500-1:3,000 |
Species reactivity | Human, Mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide sequence around phosphorylation site of threonine 568 (M-Q-T(p)-P-C) derived from Human MSK2. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 50% glycerol |
Contains | 0.02% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2610023 |
This antibody is predicted to react with mouse based on sequence homology.
RPS6KA4 (MSK2) is a serine/threonine protein kinase that is essential for the regulation of various cellular processes. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. RPS6KA4 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and c-fos. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 90 kDa ribosomal protein S6 kinase 4; EC 2.7.11.1; kinase MSK2; KS6A4; mitogen- and stress-activated protein kinase 2; mitogen- and stress-activated protein kinase-2; Nuclear mitogen- and stress-activated protein kinase 2; Ribosomal protein kinase B; ribosomal protein S6 kinase alpha 4; Ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kD, polypeptide 4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; RLSK; RSK-like protein kinase; RSKB; S6K-alpha-4
Gene Aliases: 1110069D02Rik; 90kDa; AI848992; mMSK2; MSK2; RPS6KA4; RSK-B; S6K-alpha-4
UniProt ID: (Human) O75676, (Mouse) Q9Z2B9
Entrez Gene ID: (Human) 8986, (Mouse) 56613
Molecular Function: non-receptor serine/threonine protein kinase protein modifying enzyme
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.