Invitrogen

Manufacturer Code:PA527457

PU.1 Rabbit anti-Human, Polyclonal, Invitrogen™

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PU.1 Rabbit [PA527457] — Western blot analysis of PU.1 using 30g of HeLa lysate. Samples were loaded onto a 12% SDS-PAGE gel and probed with a PU.1 polyclonal antibody (Product # PA5-27457) at a dilution of 1:1000.

Product Details

TESTED APPLICATIONS	DILUTION
Western Blot (WB)	Assay dependent

Species reactivity	Human
Host / Isotype	Rabbit
Class	Polyclonal
Type	Antibody
Immunogen	Recombit fragment corresponding to a region within amino acids 1 and 152 of Human PU.1
Conjugate	Unconjugated
Form	Liquid
Purification	purified
Storage buffer	PBS, pH7.4
Contains	15mM sodium azide
Storage conditions	Store at 4°C short term. For long term storage store at -20°C avoiding freeze/thaw cycles.

Product Specific Information

Rabbit Polyclonal Antibody

For Research Use Only

Bioinformatics

Protein Aliases: 31 kDa transforming protein; 31 kDa-transforming protein; hematopoietic transcription factor PU.1; OF PU.1 SFPI1 SPI-1 SPI-A 31 kDa transforming protein 31 kDa-transforming protein SPI-1 proto-oncogene hematopoietic transcription factor PU.1 transcription factor PU.1; spleen focus forming virus (SFFV) proviral integration oncogene spi1; Transcription factor PU.1

Gene Aliases: OF; PU.1; SFPI1; SPI-1; SPI-A; SPI1

UniProt ID: (Human) P17947

Entrez Gene ID: (Human) 6688

Molecular Function: Blue Arrow Icon nucleic acid binding signaling molecule transcription factor

Function(s)

negative regulation of transcription from RNA polymerase II promoter lymphoid progenitor cell differentiation transcription from RNA polymerase II promoter lymphocyte differentiation erythrocyte differentiation macrophage differentiation granulocyte differentiation somatic stem cell population maintenance myeloid dendritic cell differentiation histone H3 acetylation hypermethylation of CpG island negative regulation of MHC class II biosynthetic process regulation of erythrocyte differentiation negative regulation of gene expression, epigenetic negative regulation of transcription, DNA-templated positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter anatomical structure regression cellular response to ethanol negative regulation of histone H4 acetylation apoptotic process involved in patterning of blood vessels positive regulation of pri-miRNA transcription from RNA polymerase II promoter

Process(es)

RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
RNA binding
protein binding
NFAT protein binding

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PU.1 Rabbit anti-Human, Polyclonal, Invitrogen™

Product Details

Product Specific Information

Bioinformatics

Suggested Secondary Antibodies

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Material safety data sheets (MSDS)

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PU.1 Rabbit anti-Human, Polyclonal, Invitrogen™

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Product Details

Product Specific Information

Bioinformatics

Suggested Secondary Antibodies

Documents

Material safety data sheets (MSDS)

Performance Guarantee

We’re here to help

Your items have has been added!