Invitrogen
Catalog # PA5-50565
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | 1:100-1:300 |
Species reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human Platelet-derived growth factor alpha polypeptide |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 2.7 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20°C |
RRID | AB_2636018 |
The antibody detects endogenous levels of total PDGFA protein.
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit A, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit B. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PDGF A-chain; PDGF subunit A; PDGF-1; platelet derived growth factor, alpha; Platelet-derived growth factor A chain; platelet-derived growth factor A-chain; platelet-derived growth factor alpha chain; Platelet-derived growth factor alpha polypeptide; Platelet-derived growth factor subunit A
Gene Aliases: PDGF-A; PDGF1; PDGFA; PDGFACP; Rpa1
UniProt ID: (Human) P04085, (Rat) P28576, (Mouse) P20033
Entrez Gene ID: (Human) 5154, (Rat) 25266, (Mouse) 18590
Molecular Function:
growth factor
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