Invitrogen
Catalog # PA1-31124
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunoprecipitation (IP) | 1:200 |
Western Blot (WB) | 1:250-1:500 |
Species reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptides (conserved sequence near the N-terminal) unique to PDE1A family members. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.65 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | tris glycine, pH 7.4-7.9, with 30% glycerol, 0.5% BSA |
Contains | 0.02% Sodium azide |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_2162896 |
Recommended positive controls: Rat testis.
Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1)that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3'-RACE clone 8 phosphodiesterase 1A; 3-RACE clone 8 phosphodiesterase 1A; 61 kDa Cam-PDE; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; Cam-PDE 1A; Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; hCam-1; HS MGC26303; MGC26303; phosphodiesterase 1A, calmodulin-dependent; phosphodiesterase-1A
Gene Aliases: 3'-RACEclone8phosphodiesterase1A; 3-RACEclone8phosphodiesterase1A; AI987702; AW125737; CAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A; PDE1A
UniProt ID: (Human) Q9C0L2, (Mouse) Q61481
Entrez Gene ID: (Human) 5136, (Mouse) 18573, (Rat) 81529
Molecular Function: phosphodiesterase
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