Invitrogen
Catalog # PA1-9123
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (IHC) | 5 µg/mL |
Western Blot (WB) | 0.2 µg/mL |
Species reactivity | Human |
Host / Isotype | Goat / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to residues C-YHTFSAHQSRSR, from the internal region of PCSK6 |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.5 mg/mL |
Purification | Ammonium sulfate precipitation |
Storage buffer | TBS, pH 7.3, with 0.5% BSA |
Contains | 0.02% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_10986244 |
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Paired basic amino acid cleaving enzyme 4; paired basic amino acid cleaving system 4; Proprotein convertase subtilisin/kexin type 6; SPC4; Subtilisin-like proprotein convertase 4; Subtilisin/kexin-like protease PACE4
Gene Aliases: PACE4; PCSK6; SPC4
UniProt ID: (Human) P29122
Entrez Gene ID: (Human) 5046
Molecular Function:
serine protease
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