Catalog # PA1-4280
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:250-1:500 |
PUBLISHED APPLICATIONS | |
---|---|
Western Blot (WB) | See 1 publications below |
Immunohistochemistry (IHC) | See 1 publications below |
Species reactivity | Human |
Published species | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to residues Q(43) R Q E S K K M P V A G G K A N K(59) of human PARP2. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | Conc. Not Determined |
Storage buffer | whole serum |
Contains | 0.02% sodium azide |
Storage conditions | Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C |
RRID | AB_2158682 |
PA1-4280 detects the PARP-2 protein in human samples.
PA1-4280 has been successfully used in Western blot procedures. This antibody detects a ~66 kDa protein representing PARP-2 in 3T3 cell lysate.
PA1-4280 immunizing peptide corresponds to amino acid residues 43-59 of the 62 kDa human PARP-2 protein.
Store at 4ºC for 3 months or at -20ºC for longer periods.
This gene encodes polytransferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase diphtheria toxin-like 2; ADPRT-2; ARTD2; DNA ADP-ribosyltransferase PARP2; HGNC:272; hPARP-2; NAD(+) ADP-ribosyltransferase 2; pADPRT-2; parp 2; PARP-2; poly (ADP-ribose) polymerase 2; poly (ADP-ribose) polymerase family, member 2; poly (ADP-ribosyl) transferase-like 2; Poly [ADP-ribose] polymerase 2; Poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2; Protein poly-ADP-ribosyltransferase PARP2
Gene Aliases: ADPRT2; ADPRTL2; ADPRTL3; ARTD2; pADPRT-2; PARP-2; PARP2
UniProt ID: (Human) Q9UGN5
Entrez Gene ID: (Human) 10038
Molecular Function:
DNA metabolism protein
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