Invitrogen
Catalog # PA1-27969
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Frozen) (IHC (F)) | 1:100-1:1,000 |
Species reactivity | Rat |
Host / Isotype | Guinea pig / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | synthetic peptide VEKQSTDSGAYSIGH, corresponding to amino acids 383-397 of Rat P2X3. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | Conc. Not Determined |
Storage buffer | whole serum |
Contains | 0.05% sodium azide |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_1959182 |
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP receptor; MGC129956; P2X purinoceptor 3; p2X receptor 3; P2X3; p2X3 purinoceptor; p2xr3; Purinergic receptor
Gene Aliases: P2rx3
UniProt ID: (Rat) P49654
Entrez Gene ID: (Rat) 81739
Molecular Function:
ligand-gated ion channel
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