Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View details.
Catalog # PA5-49431
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Flow Cytometry (Flow) | 1:25 |
Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
Western Blot (WB) | 1:1,000 |
Immunocytochemistry (ICC/IF) | 1:25 |
PUBLISHED APPLICATIONS | |
---|---|
Flow Cytometry (Flow) | See 2 publications below |
Immunocytochemistry (ICC/IF) | See 3 publications below |
ChIP assay (ChIP) | See 2 publications below |
Immunohistochemistry (IHC) | See 3 publications below |
Western Blot (WB) | See 1 publications below |
Species reactivity | Human, Mouse |
Published species | Human, Mouse, Zebrafish |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | KLH conjugated synthetic peptide between 98-133 amino acids from the Central region of mouse Nkx2-5. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.5 mg/mL |
Purification | Protein A, Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4 |
Contains | 0.09% sodium azide |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_2634885 |
This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cardiac-specific homeobox; cardiac-specific homeobox 1; Drosophila NK2 transcription factor related, locus 5; FLJ52202; FLJ97166; FLJ97195; FLJ97197; FLJ99536; Homeobox protein CSX; Homeobox protein NK-2 homolog E; homeobox protein NKX 2-5; Homeobox protein Nkx-2.5; NK2 transcription factor related locus 5; NK2 transcription factor related, locus 5; NKX 2-5; Nkx-25; tinman paralog
Gene Aliases: CHNG5; CSX; CSX1; HLHS2; Nkx-2.5; NKX2-5; NKX2.5; NKX2E; NKX4-1; tinman; VSD3
UniProt ID: (Human) P52952, (Mouse) P42582
Entrez Gene ID: (Human) 1482, (Mouse) 18091
Molecular Function: homeodomain transcription factor
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