Invitrogen
Catalog # PA5-51216
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | 1:100-1:200 |
Western Blot (WB) | 1:200-1:1,000 |
Species reactivity | Human, Mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Full length fusion protein of human NUDT2 |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.8 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20°C |
RRID | AB_2636664 |
The antibody detects endogenous levels of total NUDT2 protein.
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and three transcript variants, all encoding the same protein, have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ap4A hydrolase; Ap4A hydrolase 1; Ap4Aase; bis(5'-nucleosyl)-tetraphosphatase; bis(5'-nucleosyl)-tetraphosphatase (asymmetrical); Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase; diadenosine 5',5''-P1,P4-tetraphosphate pyrophosphohydrolase; diadenosine tetraphosphatase; MGC10404; Nucleoside diphosphate-linked moiety X motif 2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; Nudix motif 2
Gene Aliases: 2310051L06Rik; AA939917; APAH1; NUDT2
UniProt ID: (Human) P50583, (Mouse) P56380
Entrez Gene ID: (Human) 318, (Mouse) 66401
Molecular Function:
hydrolase
metabolite interconversion enzyme
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