Invitrogen
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:1,000 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | KLH conjugated synthetic peptide between 13-40 amino acids from the N-terminal region of human NMNAT2. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | Lot-Specific |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2634294 |
Predicted to react with bovine, mouse and rat based on sequence homology.
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate but with a lower efficiency. Cannot use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity prefers NAD(+), NADH and NAAD as substrates and degrades nicotinic acid adenine dinucleotide phosphate (NHD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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