Catalog # OPA1-04021
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (IHC) | 1:1,000 |
Immunoprecipitation (IP) | 3 µL/200 µg lysate |
Western Blot (WB) | 1:1,000 |
PUBLISHED APPLICATIONS | |
---|---|
Western Blot (WB) | See 4 publications below |
Immunohistochemistry (IHC) | See 1 publications below |
Immunoprecipitation (IP) | See 3 publications below |
Immunocytochemistry (ICC/IF) | See 1 publications below |
Species reactivity | Human, Mouse, Rabbit, Rat |
Published species | Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Fusion protein from the C-terminal region of the NR2A subunit of rat GRIN2A |
Conjugate | Unconjugated |
Form | Lyophilized |
Purification | Affinity chromatography |
Storage buffer | 5mM Ammonium bicarbonate, pH 7.5 |
Contains | no preservative |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2112313 |
In Western blot, this antibody detects a single ~180 kDa protein representing NR2A in rat brain homogenate. It shows no cross-reactivity with NR2B.
Reconstitute with 50 µL of PBS.
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GluN2A; GluRepsilon1; Glutamate [NMDA] receptor subunit epsilon-1; glutamate receptor; Glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; hNR2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; NMDA Receptor 2A; NMDAR 2A; NMDAR2A; OTTHUMP00000160135; OTTHUMP00000174531
Gene Aliases: EPND; FESD; GluN2A; GRIN2A; LKS; NMDAR2A; NR2A
UniProt ID: (Human) Q12879, (Mouse) P35436, (Rat) Q00959
Entrez Gene ID: (Human) 2903, (Rabbit) 100337889, (Mouse) 14811, (Rat) 24409
Molecular Function:
transmembrane signal receptor
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.