Catalog # A-6473
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | Assay-dependent |
Immunohistochemistry (Frozen) (IHC (F)) | 1:500-1:5,000 |
Immunoprecipitation (IP) | 3 µL |
Western Blot (WB) | 1:100-1:500 |
PUBLISHED APPLICATIONS | |
---|---|
Western Blot (WB) | See 17 publications below |
Immunocytochemistry (ICC/IF) | See 3 publications below |
Immunohistochemistry (IHC) | See 2 publications below |
Miscellaneous PubMed (Misc) | See 1 publications below |
Immunoprecipitation (IP) | See 1 publications below |
Species reactivity | Human, Mouse, Rat |
Published species | Human, Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Fusion protein containing amino acid residues 1253-1391 of the C-terminal region of rat brain subunit 2A |
Conjugate | Unconjugated |
Form | Lyophilized |
Purification | IgG fraction |
Storage buffer | PBS |
Contains | no preservative |
Storage conditions | -20°C |
RRID | AB_2536209 |
This antibody recognizes the 180 kDa 2A subunit from rat, mouse and human, and does not cross-react with the 2B or 2C subunits.
Storage and reconstitution: when stored at -20ºC or below, the lyophilized antibody should retain full activity for over one year. Reconstitute using 50 µL PBS, pH 7.4, to yield a 0.2 mg/mL solution. If storing at 0-4ºC, add sodium azide to a final concentration of 2mM. For longer storage, divide the solution into aliquots and freeze at -20ºC, avoiding freeze/thaw cycles.
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GluN2A; GluRepsilon1; Glutamate [NMDA] receptor subunit epsilon-1; glutamate receptor; Glutamate receptor ionotropic, NMDA 2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; hNR2A; N-methyl D-aspartate receptor subtype 2A; N-methyl-D-aspartate receptor channel, subunit epsilon-1; N-methyl-D-aspartate receptor subunit 2A; NMDA Receptor 2A; NMDAR 2A; NMDAR2A; OTTHUMP00000160135; OTTHUMP00000174531
Gene Aliases: EPND; FESD; GluN2A; GRIN2A; LKS; NMDAR2A; NR2A
UniProt ID: (Human) Q12879, (Mouse) P35436, (Rat) Q00959
Entrez Gene ID: (Human) 2903, (Mouse) 14811, (Rat) 24409
Molecular Function:
transmembrane signal receptor
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