Invitrogen
Catalog # PA5-49695
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | 1:2,000-1:5,000 |
Immunohistochemistry (Paraffin) (IHC (P)) | 1:25-1:100 |
Western Blot (WB) | 1:500-1:2,000 |
Species reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Fusion protein corresponding to a region derived from 1-221 amino acids of human nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.9 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2635148 |
The antibody detects endogenous level of total NFKBID protein.
May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.I-kappa-BNS, the nuclear I-kappa-B-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.I-kappa-BNS has been identified as a member of the I-kappa-B family of NF-kappa-B inhibitors, which undergoes induction upon TCR signaling. I-kappa-BNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: I-kappa-B-delta; ikappaBdelta; IkappaBNS; IkB-delta; NF-kappa-B inhibitor delta; NFKB inhibitor delta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta; T-cell activation NFKB-like protein; TA-NFKBH
Gene Aliases: IkappaBNS; IKBNS; NFKBID; TA-NFKBH
UniProt ID: (Human) Q8NI38
Entrez Gene ID: (Human) 84807
Molecular Function:
protein-binding activity modulator
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