Invitrogen
Catalog # PA1-4198
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:500-1:1,000 |
Species reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to residues A(269) S P Q R S R S P S P Q P(281) of human NFATc2. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS |
Contains | 0.02% sodium azide |
Storage conditions | Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C |
RRID | AB_560295 |
PA1-4198 detects NFAT2 in human samples. NFATc2 is also known as NFAT1 or NFATp.
PA1-4198 has been successfully used in Western blot procedures.
The PA1-4198 immunogen is a synthetic peptide corresponding to residues A(269) S P Q R S R S P S P Q P(281) of human NFATc2.
The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3). These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IB-IXL; KIAA0611; NF-ATc2; NF-ATp; NFAT pre-existing s; NFAT pre-existing subunit; NFAT transcription complex, preexisting component; Nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, preexisting component; OTTHUMP00000031291; preexisting nuclear factor of activated T-cells 2; T cell transcription factor NFAT1; T-cell transcription factor NFAT1
Gene Aliases: NFAT1; NFATC2; NFATP
UniProt ID: (Human) Q13469
Entrez Gene ID: (Human) 4773
Molecular Function:
Rel homology transcription factor
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