Catalog # MA1-25479
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
Western Blot (WB) | 1:1,000 |
PUBLISHED APPLICATIONS | |
---|---|
Immunohistochemistry (IHC) | See 1 publications below |
Western Blot (WB) | See 1 publications below |
ELISA (ELISA) | See 1 publications below |
Species reactivity | Horse, Fish, Human, Mouse, Rabbit, Rat |
Published species | Human, Rat |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Clone | UC1MT |
Immunogen | Full length protein from cross linked rabbit liver MT1 and MT2. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | Protein G |
Storage buffer | PBS, pH 7.2, with 50% glycerol |
Contains | 0.09% sodium azide |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_794848 |
A band of approximately 15 kDa is detected.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene is a member of the metallothionein family of genes. Proteins encoded by this gene family are low in molecular weight, are cysteine-rich, lack aromatic residues, and bind divalent heavy metal ions. The conserved cysteine residues co-ordinate metal ions using mercaptide linkages. These proteins act as anti-oxidants, protect against hydroxyl free radicals, are important in homeostatic control of metal in the cell, and play a role in detoxification of heavy metals. Disruption of two metallothionein genes in mouse resulted in defects in protection against heavy metals, oxidative stress, immune reactions, carcinogens, and displayed obesity. MT1A (Metallothionein 1A) is a Protein Coding gene. Diseases associated with MT1A include Menkes Disease and Deficiency Anemia. Among its related pathways are Metal ion SLC transporters and Cellular responses to stimuli. An important paralog of this gene is MT2A.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: metallothionein 1A (functional); metallothionein 1S; Metallothionein-1A; Metallothionein-IA; MT-1A; MT-IA
Gene Aliases: MT-1A; MT-IA; MT1; MT1A; MT1S; MTC
UniProt ID: (Rabbit) P11957, (Human) P04731
Entrez Gene ID: (Rabbit) 100343802, (Human) 4489
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