Catalog # HYB 131-18-02
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | 1:16,000 |
Western Blot (WB) | Assay-dependent |
PUBLISHED APPLICATIONS | |
---|---|
Dot blot (DB) | See 1 publications below |
Published species | Not Applicable |
Host / Isotype | Mouse / IgG1, kappa |
Class | Monoclonal |
Type | Antibody |
Clone | 11F11 |
Immunogen | Human MBL. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Storage conditions | 4° C, store in dark |
RRID | AB_2281607 |
HYB 131-18-02 is specific for human MBL from plasma or serum, but cross-reacts with MBL from rat.
HYB 131-18-02 has been successfully used in ELISA and Western blotting procedures. HYB 131-18-02 reacts with rat serum, when captured on an mannan coat in ELISA.
The HYB 131-18-02 immunogen is human MBL.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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