Invitrogen
Catalog # PA1-24778
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Neutralization (Neu) | 0.05-0.20 µg/mL |
Western Blot (WB) | 0.1-2 µg/mL |
Species reactivity | Human |
Host / Isotype | Goat / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Purified, recombinant human IFN-beta, expressed in E. coli. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.1 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS |
Contains | no preservative |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_794534 |
PA1-24778 has been successfully used in Western blot procedures, where a band of approximately 224 kDa is predicted to be detected.
Type I Interferons (IFN-alpha/beta) are produced primarily in response to viral infection by Natural IFN-producing cells (IPCs) as part of the host immune response. IFNs can also inhibit the development of tumors. IFN-beta binding results in the activation of the tyrosine kinases Jak1 and Tyk2, phosphorylation of members of the STAT family of transcription factors, and the transcription and expression of the immune response genes. More recently, several members of the toll-like receptor (TLR) family were found to stimulate the production IFN-beta. IFN-beta is currently used clinically for treatment of tumors, infections and multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Fibroblast interferon; IFN b; IFN β; IFN-beta; IFNbeta; IFNβ; Interferon b; Interferon beta; interferon, beta 1, fibroblast; interferon-beta; RP11-113D19.1
Gene Aliases: IFB; IFF; IFN-beta; IFNB; IFNB1
UniProt ID: (Human) P01574
Entrez Gene ID: (Human) 3456
Molecular Function:
interferon superfamily
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