Invitrogen
Catalog # A21976
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | Assay-dependent |
Immunoprecipitation (IP) | Assay-dependent |
Immunocytochemistry (ICC/IF) | 4 µg/mL |
Species reactivity | Human |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Clone | 9F5AB9 |
Immunogen | Human Hydroxymethylglutaryl-CoA lyase |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | purified |
Storage buffer | HEPES buffered saline |
Contains | 0.02% sodium azide |
Storage conditions | 4° C |
RRID | AB_2535888 |
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-hydroxy-3-methylglutarate-CoA lyase; 3-hydroxy-3-methylglutaryl-CoA lyase; 3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase; HL; HMG-CoA lyase; hydroxymethylglutaricaciduria; Hydroxymethylglutaryl-CoA lyase, mitochondrial; mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
Gene Aliases: HL; HMGCL
UniProt ID: (Human) B7UCC6
Entrez Gene ID: (Human) 3155
Molecular Function:
lyase
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.