Invitrogen
This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. View details.
Catalog # PA1-4659
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:500-1:1,000 |
PUBLISHED APPLICATIONS | |
---|---|
Western Blot (WB) | See 5 publications below |
Species reactivity | Rat |
Published species | Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to amino acid residues specific to rat GluR2 conjugated to KLH |
Conjugate | Unconjugated |
Form | Liquid |
Purification | Affinity chromatography |
Storage buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
Contains | no preservative |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2113757 |
This antibody is predicted to react with chicken, human, mouse, non-human primate and zebrafish based on 100% sequence homology.
This antibody is specific for the ~100 kDa GluR2 protein.
The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AMPA-selective glutamate receptor 2; GluA2; GluR-2; GluR-B; GluR-K2; glutamate receptor; Glutamate receptor 2; glutamate receptor B; Glutamate receptor ionotropic, AMPA 2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943
Gene Aliases: GluA2; gluR-B; GluR-K2; GluR2; Gria2
UniProt ID: (Rat) P19491
Entrez Gene ID: (Rat) 29627
Molecular Function:
transmembrane signal receptor
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