Catalog # PA5-48256
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Flow Cytometry (Flow) | 1:10-1:50 |
Western Blot (WB) | 1:1,000 |
PUBLISHED APPLICATIONS | |
---|---|
Western Blot (WB) | See 1 publications below |
Species reactivity | Human, Mouse |
Published species | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | KLH conjugated synthetic peptide between 173-202 amino acids from the C-terminal region of human GFER. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 2 mg/mL |
Purification | Ammonium sulfate precipitation |
Storage buffer | PBS, pH 7.4 |
Contains | 0.09% sodium azide |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_2633714 |
Isoform 1: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re- oxidized by donating electrons to cytochrome c or molecular oxygen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Augmenter of liver regeneration; ERV1 homolog; erv1-like growth factor; FAD-linked sulfhydryl oxidase ALR; hepatic regenerative stimulation substance; Hepatopoietin; hepatopoietin protein; hERV1
Gene Aliases: ALR; ERV1; GFER; HERV1; HPO; HPO1; HPO2; HSS; MNCb-0663
UniProt ID: (Human) P55789, (Mouse) P56213
Entrez Gene ID: (Human) 2671, (Mouse) 11692
Molecular Function:
oxidase
oxidoreductase
metabolite interconversion enzyme
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