Invitrogen
Catalog # MA1-43011
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | 5-10 µg/mL |
Radioimmune Assays (RIA) | Assay-dependent |
Western Blot (WB) | 5 µg/mL |
Species reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Clone | 5031 |
Immunogen | Human factor VII/VIIa. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 14.1 mg/mL |
Purification | Ion-exchange chromatography, Ammonium sulfate precipitation |
Storage buffer | 50% water with 50% glycerol |
Contains | no preservative |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_1074331 |
MA1-43011 detects Factor VII in human samples.
MA1-43011 has successfully been used in radioimmunassays, western blot and ELISA applications.
MA1-43011 was derived from human factor VII, factor VIIa and BFPRck factor VIIa.
Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; Factor 7; Factor7; FVII coagulation protein; Proconvertin; Serum prothrombin conversion accelerator; SPCA
Gene Aliases: F7; SPCA
UniProt ID: (Human) P08709
Entrez Gene ID: (Human) 2155
Molecular Function:
serine protease
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