Catalog # PA1-43041
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | 5-10 µg/mL |
Western Blot (WB) | 25 µg/mL |
PUBLISHED APPLICATIONS | |
---|---|
Western Blot (WB) | See 1 publications below |
Species reactivity | Human |
Published species | Not Applicable |
Host / Isotype | Sheep / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Human Factor V. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 9.9 mg/mL |
Purification | Ammonium sulfate precipitation, Ion-exchange chromatography |
Storage buffer | 50% water with 50% glycerol |
Contains | no preservative |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_1074327 |
PA1-43041 detects Factor V in human samples.
PA1-43041 has successfully been used in Western blot and ELISA applications.
PA1-43041 was derived from human factor V.
Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The active factor V is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in the Factor V gene can result various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, Ischemic stroke, and recurrent pregnancy loss.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activated protein C cofactor; Coagulation factor V; coagulation factor V (proaccelerin, labile factor); coagulation factor V jinjiang A2 domain; Factor 5; factor V Leiden; Factor5; Proaccelerin, labile factor
Gene Aliases: F5; FVL; PCCF; RPRGL1; THPH2
UniProt ID: (Human) P12259
Entrez Gene ID: (Human) 2153
Molecular Function:
oxidase
oxidoreductase
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