Invitrogen
Catalog # PA1-30182
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | 1 µg/mL |
Inhibition Assays (IA) | Assay-dependent |
Immunohistochemistry (Paraffin) (IHC (P)) | 5-15 µg/mL |
Neutralization (Neu) | Assay-dependent |
Western Blot (WB) | 1 µg/mL |
Species reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Recombinant full length protein (Human), expressed in CHO cells. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | IgG fraction |
Storage buffer | PBS |
Contains | no preservative |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_2246494 |
PA1-30182 has been tested for its ability to neutralize the biological activity of EPO on the human cell line, TF1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Erythropoietin (EPO) protein is a growth factor essential for the survival, proliferation, and differentiation of erythroid precursors. EPO is not responsible for early commitment to the lineage, and instead induces the final maturation of partially differentiated erythroid cells and the production of red cell-specific proteins, such as hemoglobin. The EPO receptor (EPOR) is present in higher levels on precursor cells, and expression diminishes with cell maturation.Hepatocytes are the main source of EPO in the fetus, followed by interstitial cells of the kidney after birth and through adulthood. EPO expression is upregulated during hypoxia, and low levels of transcription have also been detected in lung and brain tissue under these conditions. Recent data suggest that EPO may also play a role in the protection of neuronal tissue from damage and initiation of repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epoetin; Erythropoietin; MGC138142
Gene Aliases: EP; EPO; MVCD2
UniProt ID: (Human) P01588
Entrez Gene ID: (Human) 2056
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