Invitrogen
Catalog # PA5-49237
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:1,000 |
Species reactivity | Mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | KLH conjugated synthetic peptide between 624-650 amino acids from the C-terminal region of mouse Dab2. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.5 mg/mL |
Purification | Protein A, Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4 |
Contains | 0.09% sodium azide |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_2634693 |
Predicted to react with rat based on sequence homology.
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain. The down-regulation of DAB2 may play an important role in ovarian carcinogenesis. This gene was initially named DOC2 (for Differentially expressed in Ovarian Cancer) and is distinct from the DOC2A and DOC2B genes (for double C2-like domains, alpha and beta).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adaptor molecule disabled-2; Differentially expressed in ovarian carcinoma 2; Disabled homolog 2; DOC-2; FLJ26626; Mitogen-responsive phosphoprotein
Gene Aliases: 5730435J12Rik; AA960054; AI957090; D15Wsu122e; D630005B22Rik; Dab2; Doc-2; Doc2; p96
UniProt ID: (Mouse) P98078
Entrez Gene ID: (Mouse) 13132
Molecular Function:
scaffold/adaptor protein
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