Invitrogen
Catalog # PA1-4270
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:500 |
Species reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic Peptide: Q(399) D K I F Q G N K D Y H K D V R N N(416) |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS |
Contains | 0.02% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2089741 |
PA1-4270 detects ESDN from human, mouse and rat samples.
PA1-4270 has been successfully used in Western blot procedures.
PA1-4270 immunizing peptide corresponds to amino acid residues 399-416 from mouse and rat ESDN protein.
This protein is a key enzyme in the catabolic pathway of odd-chain fatty acids, isoleucine, threonine, methionine, and valine. It is probably a dodecamer composed of six biotin-containing alpha subunits and six beta subunits. The protein is located in the mitochondrial matrix. Defects in PCCA are the cause o fpropionic acidemia type I (PA-1) [MIM:606054]. PA-1 is a life-threatening disease characterized by episodic vomiting, lethargy and ketosis, neutropenia, periodic thrombocytopenia, hypogammaglobulinemia, develop-mental retardation, and intolerance to protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 1700055P21Rik; coagulation factor V/VIII-homology domains protein 1; CUB, LCCL and coagulation factor V/VIII-homology domains protein 1; discoidin; Discoidin, CUB and LCCL domain-containing protein 2; Endothelial and smooth muscle cell-derived neuropilin-like protein
Gene Aliases: 1700055P21Rik; AW146002; CLCP1; DCBLD2; ESDN
UniProt ID: (Human) Q96PD2, (Mouse) Q91ZV3, (Rat) Q91ZV2
Entrez Gene ID: (Human) 131566, (Mouse) 73379, (Rat) 155696
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