Invitrogen
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (IHC) | 1:1,000 |
Western Blot (WB) | 1:1,000 |
Immunocytochemistry (ICC/IF) | Assay-dependent |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | A synthetic peptide from human Cathelicidin conjugated to blue carrier protein has been used as the antigen. |
Conjugate | Unconjugated |
Form | Lyophilized |
Concentration | Conc. Not Determined |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
RRID | AB_1089751 |
Glycerol (1:1) may be added for additional stability.
Reconstitute with 150 µL of distilled water.
OSC00009W can be used with blocking peptide GSC00002P.
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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