Invitrogen
Catalog # MA1-22705
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Affinity Purification (AP) | Assay-dependent |
ELISA (ELISA) | Assay-dependent |
Species reactivity | Human |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Clone | 9G6 |
Immunogen | Full length native protein (purified) (Human). |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 5.6 mg/mL |
Purification | Protein A |
Storage buffer | PBS, pH 7.4 |
Contains | 0.09% sodium azide |
Storage conditions | 4° C, do not freeze |
RRID | AB_561849 |
MA1-22705 detects Cardiac Troponin T in Human samples.
Cardiac Troponin T is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Cardiac Troponin T is important in proper muscle function and myofibril formation. In the human heart, four cTnT isoforms are expressed in a developmentally regulated manner. Cardiac Troponin T expression in the human heart is affected by heart failure. Mutations within the Cardiac Troponin T protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the Cardiac Troponin T gene undergo alternative splicing that results in many tissue-specific isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cardiac muscle troponin T; cardiomyopathy, dilated 1D (autosomal dominant); cardiomyopathy, hypertrophic 2; cTnT; MGC3889; TnTc; troponin T type 2 (cardiac); Troponin T, cardiac muscle; Troponin T2; troponin T2, cardiac; truncated cardiac troponin T
Gene Aliases: CMD1D; CMH2; CMPD2; cTnT; LVNC6; RCM3; TNNT2; TnTC
UniProt ID: (Human) Q99597
Entrez Gene ID: (Human) 7139
Molecular Function:
actin binding motor protein
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