Test
Invitrogen
Catalog # LF-MA0229
Quantity:
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Shared lists are a new way to save products. Create a list for each of your projects to share with collaborators like your lab manager. Then select and buy products as a team.
Click "Save to list" to create your first list, give it a name, and add the product. Access your shared lists in the Account link on Thermofisher.com.
You can invite collaborators like your lab manager or procurement staff to any shared list. They can add more items, leave comments and complete the final purchase.
Export your list as a spreadsheet for easy documentation or hand off to your lab’s designated buyer.
Shared lists are a new way to save products. Create a list for each of your projects to share with collaborators like your lab manager. Then select and buy products as a team.
Creating a shared list
Click "Save to list" to create your first list, give it a name, and add the product. Access your shared lists in the Account link on Thermofisher.com. |
Collaborate
You can invite collaborators like your lab manager or procurement staff to any shared list. They can add more items, leave comments and complete the final purchase. |
Export your list as a spreadsheet for easy documentation or hand off to your lab’s designated buyer.
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TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | Assay-dependent |
Immunoprecipitation (IP) | 2 µL |
Western Blot (WB) | 1:2,000 |
Host / Isotype | Mouse / IgG2b |
Class | Monoclonal |
Type | Antibody |
Clone | 3D10 |
Immunogen | Recombinant Human protein purified from E.coli(His-Troponin I(partial)) |
Conjugate | Unconjugated |
Form | Liquid |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_1961145 |
A suggested positive control for this product is human Troponin I protein.
Cardiac Troponin I (Cardiac-specific troponin I, TnI, Troponin I) is an integral inhibitory protein in cardiac muscle that exists as part of a complex with troponin C (TnC) and troponin T (TnT). The TnT subunit of troponin binds to tropomyosin-t form, a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, anabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurements of blood TnI and TnT levels is an important diagnostics indicator of heart muscle damage, and can be used to differentiate between angina and myocardial infarction in patients with chest pains. Cardiac Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro. Mutations in the Cardiac Troponin I gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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