Invitrogen
Catalog # PA1-31217
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
Immunoprecipitation (IP) | 1:250 |
Western Blot (WB) | 1:500 |
Immunocytochemistry (ICC/IF) | 1:200 |
Species reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide: EDLSNYSYSSTLPPFLLDAAPC Corresponding to amino acids 18-39 of Human CXCR2. |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.75 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | tris glycine, pH 7.4-7.9, with 0.5% BSA, 30% glycerol |
Contains | 0.02% sodium azide |
Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID | AB_2126488 |
Predicted molecular weight of 55 kDa.
CXCR2 is a receptor for interleukin-8, which is a powerful neutrophil chemotactic factor. It is a member of the GPCR family. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to GRO/MGSA and NAP-2 also with a high affinity. It has been reported to be expressed in a wide variety of tissues. ESTs have been isolated from human placenta and thymus libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C Cmotif chemokine; C X C motif chemokine; C-X-C chemokine receptor type 2; CC motif chemokine; CCmotif chemokine; CD182; CD182 antigen; CDw128b; chemokine (C-X-C motif) receptor 2; chemokine (C-X-C) receptor 2; chemokine (CXC) receptor 2; CXC; CXC motif chemokine; CXC-R2; CXCR-2; CXCR2 gene for IL8 receptor type B; GRO/MGSA receptor; High affinity interleukin-8 receptor B; IL-8 receptor alpha chain; Il-8 receptor b; IL-8 receptor beta; IL-8 receptor type 2; IL-8R B; interleukin 8 receptor B; interleukin 8 receptor type 2; interleukin 8 receptor, beta; interleukin-8 receptor type B
Gene Aliases: CD128; CD182; CDw128; CDw128b; CMKAR2; CXCR2; Gpcr16; IL-8rb; IL-8Rh; IL8R2; IL8RA; IL8RB; mIL-8RH
UniProt ID: (Human) P25025, (Mouse) P35343, (Rat) P35407
Entrez Gene ID: (Human) 3579, (Mouse) 12765, (Rat) 29385
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