Invitrogen
Catalog # PA5-50490
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:500-1:2,000 |
Species reactivity | Human, Mouse, Rat |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human Cholinergic receptor muscarinic 4 |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1.6 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20°C |
RRID | AB_2635943 |
The antibody detects endogenous levels of total CHRM4 protein.
Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acetylcholine receptor; acetylcholine receptor, muscarinic 4; AChR M4; cholinergic receptor; cholinergic receptor, muscarin 4; cholinergic receptor, muscarinic 4; Mm4 mAChR; muscarinic acetylcholine receptor 4; Muscarinic acetylcholine receptor M4
Gene Aliases: Chrm-4; CHRM4; HM4; M4; M4R
UniProt ID: (Human) P08173, (Mouse) P32211, (Rat) P08485
Entrez Gene ID: (Human) 1132, (Mouse) 12672, (Rat) 25111
Molecular Function:
G-protein coupled receptor
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