Catalog # PA5-50527
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Western Blot (WB) | 1:500-1:2,000 |
PUBLISHED APPLICATIONS | |
---|---|
Western Blot (WB) | See 1 publications below |
Flow Cytometry (Flow) | See 1 publications below |
Species reactivity | Human, Mouse |
Published species | Human, Mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human Solute carrier family 1 (neutral amino acid transporter), member 5 |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 1.2 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20°C |
RRID | AB_2635980 |
The antibody detects endogenous levels of total SLC1A5 / ASCT2 protein.
SLC1A5 (Solute carrier family 1 (neutral amino acid transporter), member 5) is a member of the Na(+)-dependent amino acid transporter superfamily. It has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. It acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ASC-like Na(+)-dependent neutral amino acid transporter ASCT2; ATB(0); ATB0; Baboon M7 virus receptor; insulin-activated amino acid transporter; neutral amino acid transporter B; Neutral amino acid transporter B(0); RD114 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; solute carrier family 1 (neutral amino acid transporter), member 5; Solute carrier family 1 member 5; solute carrier family 1, member 7
Gene Aliases: AAAT; ASCT2; ATBO; M7V1; M7VS1; R16; RDR; RDRC; SLC1A5; Slc1a7
UniProt ID: (Human) Q15758
Entrez Gene ID: (Human) 6510, (Mouse) 20514
Molecular Function: primary active transporter
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