Catalog # PA3-210
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Western Blot (WB) | 1:5,000 |
Immunocytochemistry (ICC/IF) | 1:250 |
PUBLISHED APPLICATIONS | |
---|---|
Immunohistochemistry (IHC) | See 1 publications below |
Western Blot (WB) | See 1 publications below |
Species reactivity | Human |
Published species | Human, Mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to the C-terminal amino acids C(349)RKSSSLREMETFVS(363) of AGTR2 |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | Conc. Not Determined |
Storage buffer | whole serum |
Contains | 0.02% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_11007512 |
PA3-210 detects AGTR2 in human samples.
PA3-210 has successfully been used in Western blot, immunocytochemical, and immunohistochemical (paraffin) procedures.
The PA3-210 immunogen is a synthetic peptide corresponding to the C-terminal amino acids C(349)RKSSSLREMETFVS(363) of AGTR2
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Angiotensin ii at2; angiotensin II receptor, type 2; Angiotensin II type-2 receptor; AT2 receptor; Type-2 angiotensin II receptor
Gene Aliases: AGTR2; AT2; ATGR2; MRX88
UniProt ID: (Human) P50052
Entrez Gene ID: (Human) 186
Molecular Function:
G-protein coupled receptor
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