Invitrogen
Catalog # PA5-40075
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
ELISA (ELISA) | 1:3,500 |
Western Blot (WB) | 1:1,000 |
Species reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of both EIF2C1 and EIF2C2 corresponding to human IEF2C1/2 (eukaryotic translation initiation factor 2C1 and 2). |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | Conc. Not Determined |
Storage buffer | whole serum |
Contains | 0.05% sodium azide |
Storage conditions | -20° C, Avoid Freeze/Thaw Cycles |
RRID | AB_2576597 |
IEF2C1 and 2 are members of the Argonaute family. These proteins are involved in short-interfering-RNA-mediated gene silencing. This process is mediated by the RISC (RNA induced silencing complex), a multicomponent nuclease that is able to degrade double stranded RNAs. The mRNA degradation is triggered by the association of specific siRNAs with their homologous mRNAs. IEF2C2 has been shown to be essential for embryonic development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: argonaute 1; argonaute 2; Argonaute RISC catalytic component 1; Argonaute RISC catalytic component 2; Argonaute1; Argonaute2; CTA-204B4.6; eIF-2C 1; eIF-2C 2; eIF2C 1; eIF2C 2; Eukaryotic translation initiation factor 2C 1; Eukaryotic translation initiation factor 2C 2; eukaryotic translation initiation factor 2C, 1; eukaryotic translation initiation factor 2C, 2; Golgi Endoplasmic Reticulum protein 95 kDa; hAgo2; PAZ Piwi domain protein; PPD; Protein argonaute-1; Protein argonaute-2; Protein slicer; Putative RNA-binding protein Q99
Gene Aliases: AGO1; AGO2; EIF2C; EIF2C1; EIF2C2; GERP95; hAgo1; Q10; Q99
UniProt ID: (Human) Q9UL18, (Human) Q9UKV8
Entrez Gene ID: (Human) 26523, (Human) 27161
Molecular Function: translation initiation factor
If an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.