Catalog # PA5-50297
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | 1:25-1:100 |
Western Blot (WB) | 1:200-1:1,000 |
PUBLISHED APPLICATIONS | |
---|---|
Immunocytochemistry (ICC/IF) | See 1 publications below |
Species reactivity | Human, Mouse |
Published species | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Fusion protein corresponding to residues near the C terminal of human Acyl-CoA oxidase 2, branched chain |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.2 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20°C |
RRID | AB_2635750 |
The antibody detects endogenous levels of total ACOX2 protein.
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe mental retardation, and death in children.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase; 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase; acyl-CoA oxidase 2, branched chain; acyl-Coenzyme A oxidase 2, branched chain; branched chain acyl-CoA oxidase; Peroxisomal acyl-coenzyme A oxidase 2; peroxisomal branched chain acyl-CoA oxidase; THCA-CoA oxidase; Trihydroxycoprostanoyl-CoA oxidase
Gene Aliases: ACOX2; BCOX; BRCACOX; BRCOX; THCCox
UniProt ID: (Human) Q99424, (Mouse) Q9QXD1
Entrez Gene ID: (Human) 8309, (Mouse) 93732
Molecular Function:
oxidoreductase
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