Invitrogen
Catalog # PA5-50481
Quantity:
TESTED APPLICATIONS | DILUTION |
---|---|
Immunohistochemistry (Paraffin) (IHC (P)) | 1:25-1:100 |
Species reactivity | Human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Synthetic peptide corresponding to residues near the C terminal of human Apoptosis-associated tyrosine kinase |
Conjugate | Unconjugated |
Form | Liquid |
Concentration | 0.8 mg/mL |
Purification | Antigen affinity chromatography |
Storage buffer | PBS, pH 7.4, with 40% glycerol |
Contains | 0.05% sodium azide |
Storage conditions | -20°C |
RRID | AB_2635934 |
The antibody detects endogenous levels of total AATK protein.
The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AATYK; Apoptosis-associated tyrosine kinase; Brain apoptosis-associated tyrosine kinase; CDK5-binding protein; Lemur tyrosine kinase 1; p35-binding protein; p35BP; protein phosphatase 1, regulatory subunit 77; Serine/threonine-protein kinase LMTK1
Gene Aliases: AATK; AATYK; AATYK1; KIAA0641; LMR1; LMTK1; p35BP; PPP1R77
UniProt ID: (Human) Q6ZMQ8
Entrez Gene ID: (Human) 9625
Molecular Function:
non-receptor serine/threonine protein kinase
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