Triethylamine trihydrofluoride, ca 37% HF, Thermo Scientific Chemicals

Description

Triethylamine trihydrofluoride acts as a mild and selective fluorinating agent used in the synthesis of acid fluorides and alkyl fluorides. It is also used in the synthesis of vicinal difluorides from epoxides, 3-fluoroazetidine. It is utilized as a selective reagent for the cleavage of O-silyl groups in carbohydrates, nucleotides and cyanohydrins. It is actively involved in the electrochemical fluorodeiodination of alkyl iodides and fluorodesilylation in beta-lactams.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Triethylamine trihydrofluoride acts as a mild and selective fluorinating agent used in the synthesis of acid fluorides and alkyl fluorides. It is also used in the synthesis of vicinal difluorides from epoxides, 3-fluoroazetidine. It is utilized as a selective reagent for the cleavage of O-silyl groups in carbohydrates, nucleotides and cyanohydrins. It is actively involved in the electrochemical fluorodeiodination of alkyl iodides and fluorodesilylation in beta-lactams.

Solubility
Miscible with water, chloroform and hexanes.

Notes
Hygroscopic. Incompatible with strong oxidizing agents and glass.

Specifications

• Melting Point: -29°C
• Density: 0.99
• Boiling Point: 70°C (15 mmHg)
• Flash Point: 87°C (188°F)
• Refractive Index: 1.3915
• Linear Formula: (CH₃CH₂)₃N·3HF
• Quantity: 100 g
• UN Number: UN1790
• Beilstein: 5522945
• Sensitivity: Hygroscopic
• Solubility Information: Miscible with water,chloroform and hexanes.
• Formula Weight: 161.21
• Assay: ≈37% HF
• Chemical Name or Material: Triethylamine trihydrofluoride

Safety and Handling

Hazard Category	H227-H300+H310+H330-H314-H335
Hazard Statement	GHS H Statement H300-H310-H330-H314-H318-H227 Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. Combustible liquid.
Precautionary Statement	P210-P235-P260-P262-P264b-P270-P271-P280-P284-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: HYDROFLUORIC ACID
EINECSNumber	277-550-5
TSCA	Yes
Recommended Storage	Ambient temperatures; Store under Nitrogen

SDS

RUO – Research Use Only