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  7. 2-Mercapto-5-methoxybenzimidazole, 99%, Thermo Scientific Chemicals

2-Mercapto-5-methoxybenzimidazole, 99%, Thermo Scientific Chemicals

Catalog Number AAB2057022
Click to view available options
Quantity:
5 g
25 g
100 g
37052-78-1
C8H8N2OS
180.23
MFCD00134581
KOFBRZWVWJCLGM-UHFFFAOYSA-N
5-methoxy-2-mercaptobenzimidazole, 2-mercapto-5-methoxybenzimidazole, 5-methoxy-1h-benzo d imidazole-2-thiol, 5-methoxy-2-benzimidazolethiol, 5-methoxy-1h-benzimidazole-2-thiol, 5-methoxy-1h-1,3-benzodiazole-2-thiol, 2-mercapto-5-methoxy-1h-benzimidazole, 5-methoxy-1h-benzoimidazole-2-thiol, 1,3-dihydro-5-methoxy-2h-benzimidazole-2-thione, 5-methoxybenzimidazole-2-thiol
665603
COC1=CC=C2NC(=S)NC2=C1
37052-78-1
C8H8N2OS
180.23
MFCD00134581
KOFBRZWVWJCLGM-UHFFFAOYSA-N
5-methoxy-2-mercaptobenzimidazole, 2-mercapto-5-methoxybenzimidazole, 5-methoxy-1h-benzo d imidazole-2-thiol, 5-methoxy-2-benzimidazolethiol, 5-methoxy-1h-benzimidazole-2-thiol, 5-methoxy-1h-1,3-benzodiazole-2-thiol, 2-mercapto-5-methoxy-1h-benzimidazole, 5-methoxy-1h-benzoimidazole-2-thiol, 1,3-dihydro-5-methoxy-2h-benzimidazole-2-thione, 5-methoxybenzimidazole-2-thiol
665603
COC1=CC=C2NC(=S)NC2=C1

Description

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

Solubility
Soluble in dimethyl sulfoxide. Slightly soluble in methanol. Insoluble in water.

Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents, acids, bases and reducing agents.
TRUSTED_SUSTAINABILITY
Melting Point 255°C to 259°C
Quantity 100 g
Beilstein 3605123
Solubility Information Soluble in dimethyl sulfoxide. Slightly soluble in methanol. Insoluble in water.
IUPAC Name 5-methoxy-1,3-dihydrobenzimidazole-2-thione
Formula Weight 180.23
Percent Purity 99%
Chemical Name or Material 2-Mercapto-5-methoxybenzimidazole

Safety and Handling

Hazard Category H302-H317
Hazard Statement GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Precautionary Statement P261-P264b-P270-P271-P272-P280g-P301+P312-P302+P352-P304+P340-P312-P330-P333+P313-P363-P501c
EINECSNumber 253-326-2
TSCA No
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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