Crosslinking Reagents
Crosslinking Reagents
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Filtered Search Results
Description | DSG |
---|---|
Cleavable | No |
Water Soluble | No |
Form | Powder |
Molecular Weight (g/mol) | 326.26 |
Solubility | DMF, DMSO |
Labeling Method | Chemical Labeling |
Crosslinker Type | Homobifunctional |
Chemical Reactivity | Amine-Amine |
Cell Permeability | Yes |
Format | Standard, Single-use |
Product Type | Crosslinker |
Spacer | Short (<10 Å) |
Reactive Moiety | NHS Ester |
Spacer Arm Length | 7.7 Å |
PEGylated | No |
Thermo Scientific™ PMPI (p-maleimidophenyl isocyanate)
Short (8.7A) hydroxyl-to-sulfhydryl crosslinker; isocyanate and maleimide groups; label -OH by urethane bonds for conjugation to cysteines by thioether bonds.
Thermo Scientific™ Sulfo-NHS (N-hydroxysulfosuccinimide), No-Weigh™ Format
Prepare amine-reactive sulfo-NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysulfosuccinimide, CAS 106627-54-7.
Molecular Weight (g/mol) | 217.13 |
---|---|
Solubility | Water |
PEGylated | No |
Thermo Scientific™ NHS (N-hydroxysuccinimide)
Prepare amine-reactive NHS-ester crosslinkers or enhance carbodiimide (EDC) conjugation for peptides or proteins using N-hydroxysuccinimide, CAS 6066-82-6.
Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format
Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.
Cleavable | No |
---|---|
PEGylated | No |
Thermo Scientific™ Pierce™ DSP, No-Weigh™ Format
Crosslink amines to amines with dithiobis succinimidyl propionate, composed of NHS-ester groups and disulfide-containing, 12.0A spacer arm and cleavable with reducing agents.
Content And Storage | Upon receipt store desiccated at 4°C. |
---|---|
Description | DSP |
Cleavable | By Thiols |
Water Soluble | No |
Form | Powder |
Molecular Weight (g/mol) | 404.42 |
Solubility | DMF, DMSO |
Labeling Method | Chemical Labeling |
Crosslinker Type | Homobifunctional |
Chemical Reactivity | Amine-Amine |
Cell Permeability | Yes |
Format | Standard, Single-use, Premium-grade |
Product Type | Crosslinker |
Spacer | Medium (10 to 30 Å) |
Reactive Moiety | NHS Ester |
Spacer Arm Length | 12.0 Å |
PEGylated | No |
Shipping Condition | Ambient |
---|---|
Content And Storage | Upon receipt store desiccated at 4°C. |
Description | SMCC |
Cleavable | By Thiols |
Water Soluble | No |
Form | Powder |
Molecular Weight (g/mol) | 334.32 |
Solubility | DMF, DMSO |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Sulfhydryl |
Cell Permeability | Yes |
Format | Standard, Single-use |
Product Type | Crosslinker |
Spacer | Short (<10 Å) |
Reactive Moiety | Maleimide, NHS Ester |
Spacer Arm Length | 8.3 Å |
PEGylated | No |
Thermo Scientific™ BM(PEG)3 (1,11-bismaleimido-triethyleneglycol)
Crosslink sulfhydryls to sulfhydryls (cysteine residues) with this long, pegylated, water-soluble crosslinker composed of maleimide groups and 3-unit (17.8A) PEG spacer arm.
Thermo Scientific™ Sulfo-LC-SPDP (sulfosuccinimidyl 6-(3'-(2-pyridyldithio)propionamido)hexanoate)
Crosslink amines to sulfhydryls with this water-soluble sulfo-NHS-ester and pyridyldithiol groups on 10-atom spacer arms to form cleavable disulfide bonds with cysteines.
Thermo Scientific™ SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)
Crosslink amines to sulfhydryls with this mid-length crosslinker composed of NHS-ester and maleimide groups at ends of an aromatic, 10-atom (11.6A) spacer arm.
Thermo Scientific™ GMBS (N-γ-maleimidobutyryl-oxysuccinimide ester)
Crosslink amines to sulfhydryls with this short crosslinker composed of NHS-ester and maleimide groups at ends of an aliphatic, 6-atom (7.3A) spacer arm.
Thermo Scientific™ SM(PEG)4 (PEGylated SMCC crosslinker)
Crosslink amines to sulfhydryls with these crosslinkers containing NHS-ester and maleimide groups at ends of water-soluble polyethylene glycol spacer arms (17.6 to 95.2A).
Shipping Condition | Ambient |
---|---|
Content And Storage | Upon receipt store desiccated at -20°C. |
Description | SM(PEG)4 |
Cleavable | No |
Water Soluble | Yes |
Form | Solid |
Molecular Weight (g/mol) | 513.5 |
Solubility | Water |
Labeling Method | Chemical Labeling |
Crosslinker Type | Heterobifunctional |
Chemical Reactivity | Amine-Sulfhydryl |
Cell Permeability | No |
Format | Standard |
Product Type | Crosslinker |
Spacer | Medium (10 to 30 Å) |
Reactive Moiety | Maleimide, NHS Ester |
Spacer Arm Length | 24.6 Å |
Product Line | Pierce™ |
PEGylated | Yes |
Thermo Scientific™ BS(PEG)9 (PEGylated bis(sulfosuccinimidyl)suberate)
Crosslink amines to amines with these long (21.7A and 35.8A) crosslinkers composed of NHS-ester groups and 5-unit or 9-unit PEG spacer arms that enhance protein solubility.
Thermo Scientific™ LC-SPDP (succinimidyl 6-(3(2-pyridyldithio)propionamido)hexanoate)
Crosslink amines to sulfhydryls with this crosslinker composed of NHS-ester and pyridyldithiol groups at ends of 10-atom (15.7A) spacer arm.
Thermo Scientific™ Sulfo-EGS (ethylene glycol bis(sulfosuccinimidyl succinate))
Crosslink amines to amines with a crosslinker composed of sulfo-NHS-ester groups and hydroxylamine-cleavable spacer arm; water-soluble for cell-surface protein crosslinking.