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Tocris Bioscience™ NVP ADW 742

Name: Tocris Bioscience&trade; NVP ADW 742
Brand: Tocris Bioscience&trade;
SKU: 52-475-0
Price: 1173.92 USD

ATP-competitive inhibitor of IGF1R

Supplier: Tocris Bioscience™ 5247/50

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Catalog No. 52-475-0

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Description

NVP ADW 742 is an ATP-competitive inhibitor of IGF1R (IC50 in the range of 0.1-0.2 μM). Also inhibits c-Kit kinase activity (IC50 in the range of 3-5 μM). Exhibits a synergistic effect with Imatinib (Cat. No. 5906), enhancing the sensitivity of multiple small cell lung cancer cell lines to the chemotherapeutics Etoposide (Cat. No. 1226) and Carboplatin (Cat. No. 2626).

Specifications

Purity	>99%
Product Type	NVP ADW 742
Inhibitors	NVP ADW 742

Quantity	50 mg
Molecular Weight (g/mol)	453.58

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Tocris Bioscience™ NVP ADW 742

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