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Tocris Bioscience™ Tolcapone

COMT inhibitor; also inhibits transthyretin aggregation

$127.70 - $530.00

Specifications

Chemical Name or Material (3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
CAS 134308-13-7
Synonym Tasmar, Ro 40-7592
Target Catechol O-Methyltransferase (COMT) Inhibitors
Molecular Formula C14H11NO5
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
586410
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Tocris Bioscience™
5864/10 		10 mg
Each for $127.70
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586450
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Tocris Bioscience™
5864/50 		50 mg
Each for $530.00
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Description

Description

COMT inhibitor. Inhibits both brain and peripheral COMT. Also binds transthyretin (TTR) with high affinity (Kd1 and Kd2 values are 21 and 58 nM, respectively). Inhibits TTR aggregation in human plasma and prevents TTR-induced cytotoxicity in vitro. Stabilizes TTR in mice and humans in vivo. Orally bioavailable.
Specifications

Specifications

(3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
Tasmar, Ro 40-7592
C14H11NO5
>99%
134308-13-7
Catechol O-Methyltransferase (COMT) Inhibitors
273.24
Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

SDS
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