Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Biochemical Reagents
  4. Nucleosides and Analogues
  5. Triazole ribonucleosides and ribonucleotides
  6. 450150

Ribavirin, Tocris Bioscience™

Catalog No. 450150
Click to view available options
Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Serine protease inhibitor; inhibits tryptase

Antiviral guanosine ribonucleoside analog; misincorporated into mRNA by viral-dependent RNA polymerases. Binds to and redistributes mammalian eIF4E from the nucleus to the cytoplasm (Ki ∽ 0.3 μM for the active metabolite, ribavirin triphosphate). Also inosine monophosphate dehydrogenase (IMPDH) inhibitor. Represses colony formation of primary AML-M5 progenitor cells (IC50 ∽ 1 μM); reduces disease severity in acute myeloid leukemia (AML). Inhibits cytopathic effect of SARS-CoV in Vero cells in vitro. Orally available.

Chemical Identifiers

CAS 36791-04-5
Molecular Formula C8H12N4O5
Molecular Weight (g/mol) 244.207
InChI Key IWUCXVSUMQZMFG-AFCXAGJDSA-N
Synonym ribavirin, tribavirin, virazole, rebetol, ribavirine, copegus, vilona, ribamide, ribamidil, ribasphere
PubChem CID 37542
ChEBI CHEBI:63580
IUPAC Name 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
SMILES C1=NC(=NN1C2C(C(C(O2)CO)O)O)C(=O)N

Specifications

Quantity 50 mg
Formula Weight 244.2
Percent Purity >99%
Chemical Name or Material Protein-synthesizing GTPase Compounds

Safety and Handling

Recommended Storage Store at +4°C
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.