p-Toluenesulfonamide, 98+%, Thermo Scientific Chemicals

Description

p-Toluene sulfonamide was used to prepare the precursor required for synthesis of ethyl 6-phenyl-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxylate. It act as a derivative of ammonia activated to alkylation by alkyl halides is exemplified by the synthesis of N-tosyl-2,3-dihydroisoindole from o-xylylene dibromide. It is a precursor of N-tosyl imines.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
p-Toluene sulfonamide was used to prepare the precursor required for synthesis of ethyl 6-phenyl-1-tosyl-1,2,5,6-tetrahydropyridine-3-carboxylate. It act as a derivative of ammonia activated to alkylation by alkyl halides is exemplified by the synthesis of N-tosyl-2,3-dihydroisoindole from o-xylylene dibromide. It is a precursor of N-tosyl imines.

Solubility
Soluble in water.

Notes
Store in cool, dry place, in well sealed container. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 70-55-3
• Molecular Formula: C7H9NO2S
• Molecular Weight (g/mol): 171.214
• MDL Number: MFCD00011692
• InChI Key: LMYRWZFENFIFIT-UHFFFAOYSA-N
• Synonym: p-toluenesulfonamide, 4-toluenesulfonamide, tosylamide, p-tosylamide, benzenesulfonamide, 4-methyl, p-tolylsulfonamide, toluene-4-sulfonamide, tolylsulfonamide, 4-methylbenzene-1-sulfonamide, p-toluenesulfamide
• PubChem CID: 6269
• ChEBI: CHEBI:34435
• IUPAC Name: 4-methylbenzenesulfonamide
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)N

• Melting Point: 136°C to 139°C
• Boiling Point: 221°C (10 mmHg)
• Flash Point: 202°C (395°F)
• Quantity: 250 g
• Beilstein: 472689
• Solubility Information: Soluble in water.
• Formula Weight: 171.22
• Percent Purity: ≥98%
• Chemical Name or Material: p-Toluenesulfonamide

Safety and Handling

Hazard Category	H315-H319-H335
Hazard Statement	GHS H Statement H315-H319-H335 Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Precautionary Statement	P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
EINECSNumber	200-741-1
RTECSNumber	XT5075000
TSCA	Yes
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only