Precipio™ HemeScreen BCR/ABL1 Panel-20

The HemeScreen BCR/ABL1 Panel-20 is an RUO reagent set kit used to screen for 3 major BCR/ABL1 isoforms (p190, p210, and p230) and 1 minor isoform (p203) associated with BCR/ABL1-induced leukemogenesis, including CML and ALL using HRM methods.

Supplier:  Precipio™ HS20RBCR

Catalog No. 22-021-973

Description

HemeScreen is a proprietary set of RUO (Research Use Only) reagents used to screen the wild type (Negative) from Mutated (Positive) genes in a simplified workflow relative to alternative molecular testing technologies (RT-PCR or NGS).

• Isoforms tested: p190, p203, p210, p230
• Simplified workflow and reduced chance of error
• Data capture during thermocycling
• Fast turnaround time
• Broad mutation detection (SNPs, Modifications, Indels)
• Low limits of detection
• Results are qualitative and DNA sequencing is required to identify specific isoforms
• LOD: 5%
• Assay includes Primers-Mastermix Mix and positive controls
• Requires HRM-enabled RT-PCR (example Thermo Fisher™ Quantstudio 3 or higher)

Specifications

• Content And Storage: 3 x 5 mL Tube Primer Sets, 4 x 1.5 mL Tube Mutant Controls. Store at -20°C
• For Use With (Equipment): PCR Instruments
• Quantity: 20 Samples
• Shipping Condition: Dry Ice

• Detection Method: HRM
• Includes Label or Dye: Yes
• Sensitivity: 0.95
• Target Specificity: >99%

Safety and Handling

ShelfLife : 1 Year