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Cyclophosphamide, Tocris Bioscience™

Catalog No. 409150
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Alkylating agent; chemotherapeutic

Nitrogen mustard alkylating agent and prodrug. Phosphoramide mustard (active metabolite) forms DNA cross-links leading to cell death. Inhibits aldehyde dehydrogenase 1 (ALDH1) through its degradation product acrolein. Chemotherapeutic for the treatment of breast cancer; regulates Bax and Bcl-2 expression when administered with etoposide (Cat. No. 1226) in breast cancer cell lines.

Chemical Identifiers

CAS 50-18-0
Molecular Formula C7H15Cl2N2O2P
Molecular Weight (g/mol) 261.083
InChI Key CMSMOCZEIVJLDB-UHFFFAOYSA-N
Synonym cyclophosphamide, cyclophosphamid, cyclophosphane, cytophosphan, procytox, clafen, cytoxan, endoxan, neosar, cyclophosphamidum
PubChem CID 2907
ChEBI CHEBI:4027
IUPAC Name N,N-bis(2-chloroethyl)-2-oxo-1,3,2$l^{5}-oxazaphosphinan-2-amine
SMILES C1CNP(=O)(OC1)N(CCCl)CCCl

Specifications

Quantity 50 mg
Formula Weight 261.09
Percent Purity >99%
Chemical Name or Material Cyclophosphamide

Safety and Handling

Recommended Storage Store at -20°C
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