Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Diphenylethers
  8. 310850

Bumetanide, Tocris Bioscience™

Catalog No. 310850
Click to view available options
Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Na+/2Cl-/K+ (NKCC) symporter inhibitor

Bumetanide is a loop diuretic that inhibits the Na+/2Cl-/K+ (NKCC) cotransporter. More potent than furosemide (Cat. No. 3109). Bumetanide improves electrophysiological, pathological and cognitive deficits in APOE4 knock-in mice. RNA sequencing of neurons derived from APOE4 induced pluripotent stem cell (iPSC) shows Bumetanide reverses Alzheimer's disease transcriptomic signatures.

Chemical Identifiers

CAS 28395-03-1
Molecular Formula C17H20N2O5S
Molecular Weight (g/mol) 364.416
InChI Key MAEIEVLCKWDQJH-UHFFFAOYSA-N
Synonym bumetanide, 3-butylamino-4-phenoxy-5-sulfamoylbenzoic acid, bumex, burinex, fordiuran, lunetoron, fontego, segurex, bumetanida, bumetanidum
PubChem CID 2471
ChEBI CHEBI:3213
IUPAC Name 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
SMILES CCCCNC1=C(C(=CC(=C1)C(=O)O)S(=O)(=O)N)OC2=CC=CC=C2

Specifications

Quantity 50 mg
Formula Weight 364.42
Percent Purity 98%
Chemical Name or Material Bumetanide

Safety and Handling

Recommended Storage Store at Room Temperature
Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.