Hs07489158_cn

• Gene Symbol: PIN1
• Assay Reference Genome Location: Chr.19:9841419 on build GRCh38
• Cytoband: 19p13.2

Target Gene Details

• Entrez Gene ID: 5300
• Gene Name: peptidylprolyl cis/trans isomerase, NIMA-interacting 1
• Gene Aliases: DOD, UBL5
• Location: Chr.19:9835207-9849689 on Build GRCh38
• Assay Gene Location: Within Intron 4

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
PIN1	NM_006221.3			NP_006212.1
	NR_038422.2
	NR_038830.1
	XM_011528068.2			XP_011526370.1
	AF086512.1
	AK092970.1
	AK097558.1
	AK291074.1
	BC002899.1			AAH02899.1
	BC031971.1			AAH31971.1
	BG912418.1
	BI827520.1
	BI827672.1
	BT019331.1			AAV38138.1
	CD675162.1
	CR407654.1			CAG28582.1
	U49070.1			AAC50492.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
nsv520683	Chr.19:9807553 - 9968417 on Build GRCh38	Loss	COL5A3 UBL5 OLFM2 PIN1 FBXL12

More Information

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

chaperone

Gene Ontology Categories:

Process(es)

protein peptidyl-prolyl isomerization
positive regulation of protein phosphorylation
cell cycle
regulation of mitotic nuclear division
neuron differentiation
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of protein binding
regulation of cytokinesis
negative regulation of type I interferon production
positive regulation of protein dephosphorylation
negative regulation of protein catabolic process
negative regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
synapse organization
protein stabilization
positive regulation of ubiquitin-protein transferase activity
regulation of pathway-restricted SMAD protein phosphorylation
positive regulation of cell growth involved in cardiac muscle cell development
negative regulation of ERK1 and ERK2 cascade
positive regulation of canonical Wnt signaling pathway
regulation of protein localization to nucleus
regulation of signal transduction by p53 class mediator
negative regulation of cell motility

Function(s)

peptidyl-prolyl cis-trans isomerase activity
motor activity
protein binding
beta-catenin binding
mitogen-activated protein kinase kinase binding
GTPase activating protein binding
phosphoserine binding
phosphothreonine binding