Hs06392290_cn

• Gene Symbol: DCT
• Assay Reference Genome Location: Chr.13:94450375 on build GRCh38
• Cytoband: 13q32.1

Target Gene Details

• Entrez Gene ID: 1638
• Gene Name: dopachrome tautomerase
• Gene Aliases: TRP-2, TYRP2
• Location: Chr.13:94437304-94550265 on Build GRCh38
• Assay Gene Location: Within Intron 11

Gene Symbol	Transcript Accession	Exon Location	Assay Transcript Location	Protein ID
DCT	NM_001129889.2			NP_001123361.1
	NM_001322182.1			NP_001309111.1
	NM_001322183.1			NP_001309112.1
	NM_001322184.1			NP_001309113.1
	NM_001322185.1			NP_001309114.1
	NM_001322186.1			NP_001309115.1
	NM_001922.4			NP_001913.2
	XM_011521049.1			XP_011519351.1
	XM_017020401.1			XP_016875890.1
	AK293115.1
	BC028311.1			AAH28311.1
	D17547.1			BAA04484.1
	DQ902581.1
	L18967.1			AAA20870.1
	S69231.1			AAC60627.1

Target Copy Number Variation Details

• DGV Version: Release date: 2016-05-15, GRCh GRCh38

Target Variation	Location	CNV Subtype	Genes
esv34004	Chr.13:94254283 - 94740390 on Build GRCh38	Loss	GPR180 TGDS LOC101927248 SOX21 SOX21-AS1 GPC6 DCT

More Information

Additional Information:

For this assay, SNP(s) [rs151210998] are located under a primer or probe sequence. To help evaluate the possible impact of a given SNP on your experiment, please refer to the 1000 Genomes and NCBI dbSNP databases. A higher minor allele frequency in your study population represents a higher risk to assay performance.

• Set Membership: Intragenic, Intronic, Non-exonic, DGV Variation

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

positive regulation of neuroblast proliferation
melanin biosynthetic process from tyrosine
epidermis development
ventricular zone neuroblast division
developmental pigmentation
cell development
oxidation-reduction process

Function(s)

dopachrome isomerase activity
copper ion binding
oxidoreductase activity